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A dna replication bubble forms at a specific sequence of bases called the ___________. see section 15.3 ( page 321) . a dna replication bubble forms at a specific sequence of bases called the ___________. see section 15.3 ( page 321) . topoisomerase origin of replication dna polymerase leading strand lagging strand

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The answer is the Origin of replication. The origin of replication is a particular sequence in a genome at which replication is initiated. It may involve either the replication of DNA in living organisms such as prokaryotes and eukaryotes, or that of DNA or RNA in viruses, such as double stranded RNA viruses.

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