Malaria develops resistance to anti-malarial medications due to antibiotic use. The P. falciparum malaria oarasite is evolving drug resistance.
Just two of the four adult malaria parasite species, Plasmodium falciparum & P. malariae, have been demonstrated to be resistant to anti-malarial medications currently on the market. Inadequate therapeutic treatment options of active infectious diseases, overuse of anti - malarial drugs for prophylaxis, a high level of parasite ability to adapt at the metabolic and genetic levels, as well as a massive proliferation rate which permits selection are some of the causes of resistance to malaria parasites. The causes of this pattern are unknown, but two possible explanations are tenable: earlier initiation of resistance due to more frequent migration patterns between East Africa and Asia, the region where highly resistant parasites are most frequently found; and faster spread of mutations due to higher.
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