The majority of adenovirus infections result in the common cold and other minor respiratory illnesses.
A number of ailments, including bronchitis (an inflammation of the windpipe and major airways), pneumonia (an inflammation of the lungs), skin rashes, conjunctivitis (pink eye), bladder infections, and bowel infections, can be brought on by certain infections.
Adenovirus type 5 (Ad5early )'s region 1B (E1B) encodes at least five distinct polypeptides that are created by alternative splicing of a single mRNA precursor.
E1B-19K and E1B-55K, two of these gene products, both have the ability to work with the Ad5 E1A proteins to totally convert rodent cells in culture. Strong evidence points to the two E1B proteins' ability to combat growth arrest and apoptosis, which both inhibit cell transformation.
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