Satellite cells are unselected cells that surround the cell bodies of neurons in ganglia and regulate the interstitial fluid surrounding neurons.
What are satellite cells and how do you recognize them?
- Some peripheral nervous system neurons are surrounded by satellites cells (glial cells). Although their function is not entirely known, it is believed that they maintain and protect nutrients. They might also have a role in controlling the neuronal environment and neurotransmission.
- In mammalian skeletal muscle, tissue-resident muscle stem cells, so-called satellite cells, are characterized by their location between the sarcolemma and the basement membrane and the expression of the transcription factor PAX7.
What happens when satellite cells are activated?
In response to movement or injury, quiescent satellite cells are activated to enter the cell cycle, proliferate, and eventually exit at G1 and fuse to form terminally differentiated multinucleated muscle fibers.
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