Substance is the semisolid material that suspends and supports the collagen fibers is ground substance
The ground substance is the nonfibrillar organic component of the bone matrix and it fills the space around the collagen fibrils and hydroxyapatite crystals. The ground substance contains glycoproteins, proteoglycans,and glycosaminoglycans.
Ground substance provides lubrication for collagen fibers. The components of the ground substance vary depending on the tissue. Ground substance is primarily composed of water and large organic molecules, such as glycosaminglycoprotein soglycans (GAGs), proteoglycans,
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