MTOCs bind and stabilize the minus ends of microtubules. This statement accurately describes an MTOC in the cytoplasm of an undifferentiated cell.
MTOCs can be broadly defined as sites that locate microtubule minus ends with functions including microtubule nucleation, stabilization, and/or anchoring. The most well-studied MTOC is the centrosome, a non-membrane-bound organelle composed of two centrioles surrounded by a pericentriolar substance (PCM).
In animals, MTOCs form around two structures called centrosomes at the ends of the mitotic spindle. A network of proteins called pericentrosomal matter (PCM) forms around the centrosome, transforming it into her MTOC. PCM grows around the centrosome as the cell prepares to divide and is then removed.
Complete question:
Which of these statements accurately describes an mtoc in the cytoplasm of an undifferentiated cell?
a) MTOCs bind and stabilize the minus ends of microfilaments.
b) MTOCs bind and stabilize the plus ends of microtubules.
c) MTOCs bind and stabilize the plus ends of microfilaments.
d) MTOCs bind and stabilize the minus ends of microtubules.
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