Given,
The expression is,
[tex]4x^4y^5z^8\times9x^6^{}z^6[/tex]Mutliplying the expression,
[tex]\begin{gathered} 4x^4y^5z^8\times9x^6z^6=4\times9\times x^4\times y^5\times z^8\times x^6\times z^6 \\ =36\times x^{10}\times y^5\times z^{14} \\ =36x^{10}y^5z^{14} \end{gathered}[/tex]Hence, the simplified form is 36 x^10 y^5 z^14.