After malaria is cured, the frequency of the HbS allele should decrease in regions with lots of mosquitoes because having a single HbS allele is not advantageous.
Malaria is a disease caused by the bite of the Plasmodium parasites. The symptoms of the disease are fever, chills, and flu-like conditions. The disease can damage the lungs and kidney of the infected person. If not treated on time, the disease can be fatal.
HbS is the altered form of the hemoglobin (Hbb) genotype. If both the alleles are altered, then it can result in the disease sickle cell anemia. The alteration is a mutation caused in the β globin gene of the hemoglobin.
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