What groups within the amino acid molecule are mainly responsible for the tertiary structure?

The groups that stabilize the tertiary structure of a protein are disulfide bonds.
The group that mainly stabilizes the structure are disulfide bridges, which are covalent bonds between two sulfur atoms belonging to the cysteine molecule.
Although the groups that mainly stabilize the structure are disulfide bonds, we also find other types of bonds such as nonpolar interactions, hydrogen bonds, and polarity forces. Then the tertiary structure of the protein is given as a result of all these bonds.
When these interactions between the elements that make up the structure of the tertiary protein disappear, the protein begins to destabilize since each of these links is important and, as a result, it loses its function. This is known as denaturation. We can see this process when the medium in which the protein is affected, such as an increase in temperature or a change in pH.
Therefore, we can confirm that the groups that stabilize the tertiary structure of a protein are disulfide bonds.
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