Polycythemia lung cancers can cause paraneoplastic syndrome.
Paraneoplastic syndromes occur in approximately 10% of patients with lung cancer and two of the most common are humoral hypercalcemia of malignancy (HHM) in squamous cell carcinoma and the syndrome of inappropriate antidiuretic hormone secretion (SIADH) in small cell lung cancer.
These symptoms may include difficulty in walking or swallowing, loss of muscle tone, loss of fine motor coordination, slurred speech, memory loss, vision problems, sleep disturbances, dementia, seizures, sensory loss in the limbs, and vertigo or dizziness.
Paraneoplastic syndromes are rare disorders that are triggered by an altered immune system response to a neoplasm.
They are defined as clinical syndromes involving non metastatic systemic effects that accompany malignant disease.
Peripheral neuropathy is the most common neurologic paraneoplastic syndrome.
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