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The main difference between prokaryotic and eukaryotic cells is that Eukaryotic cells have a nucleus, a membrane-bound chamber where DNA is stored, while prokaryotic cells don't.

This is the feature that formally separates the two groups. Eukaryotes usually have other membrane-bound organelles in addition to the nucleus, while prokaryotes don't.

Cells in general are small, but prokaryotic cells are really small. Typical prokaryotic cells range from 0.1 to 5.0 micrometers (μm) in diameter and are significantly smaller than eukaryotic cells, which usually have diameters ranging from 10 to 100 μm.

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