The number of ways this can be done is 151200 if they choose 6 letters without replacement from 10 distinct letters.
A permutation is the number of different ways a set can be organized; order matters in permutations, but not in combinations.
We have:
Suppose we want to choose 6 letters without replacement from 10 distinct letters.
Number of letters = 10
Number of letters need to select = 6
Order is important.
A number of ways:
C(10, 6) = 10!/(10-6)!
= 10!/(4)!
= 151200
Thus, the number of ways this can be done is 151200 if they choose 6 letters without replacement from 10 distinct letters.
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