Which Christian church featured a central-plan design with an immense hemispherical dome with pendentives over the central portal, designed by a scientist and mathematician?

Hagia Sophia

Old St. Peter's

Santa Maria Maggiore

Great Mosque at Cordoba

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Answer:

Hagia Sophia.

Explanation:

The Hagia Sophia was one of the largest Christian churches of the eastern Byzantine empire. It was built in 537 as a patriarchal cathedral for the capital city of Constantinople.

The famed Christian monument was designed by Isidore of Miletus, who was a famous scientist and mathematician, and Anthemius of Tralles. Their first commission to build the monument came from emperor Justinian I and was the first to have a hemispherical dome with pendentives over the central portal.

Thus, the correct answer is the first option.