Answer:
The correct answer is:
Artists often dedicate long hours to the pursuit of their vocation, therefore, they may without thinking about it, stay up until all hours of the night.
Explanation:
The major punctuation mark being looked out for in this exercise is the comma, and in this example, it is used to indicate positions of adequate pauses in the sentence. The following are the major uses of a comma:
a) to separate independent clauses when they are joined by the coordinating conjunctions: and, but, for, or, nor, so, yet. Example, I have submitted my work, but the teacher asked me to wait behind.
b) used after an introductory clause: introductory clauses such as; if, because, when etc. are conditions for the use of a comma.
You can look up the rules for using the comma for a better understanding.