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Regions change over time because the people that come and change that climate by coming and creating a new environment. So they might start building mines and big cities to match the regions changes. When people come they might not try and change there region or they wont care and they will change it. Location and climate have large effects on income levels and income growth through their effects on transport costs, disease burdens, and agricultural productivity, among other channels. Geography also seems to affect economic policy choices. Economic growth in a cross-section of countries.